PM inaugurates 'Kosi Rail Mahasetu', slew of rail projects for Bihar; slams slow progress under UPAPrime Minister Narendra Modi. (File)

Coronavirus India News Live Updates: Prime Minister Narendra Modi Wednesday chaired a high-level virtual meeting with Chief Ministers and Health Ministers of seven Covid-19 high burden States and UT to review Covid-19 response and management. Chief ministers of Maharashtra, Andhra Pradesh, Karnataka, Uttar Pradesh, Tamil Nadu, Delhi and Punjab attended the meeting.

With India recording 83,347 cases of the novel coronavirus in the 24 hours ending 9 am Wednesday, the total number of cases in the country crossed the 56 lakh mark to reach 5,646,011. Also, as many as 1,085 deaths during the same period took the toll to 90,020. The fatality rate is 1.60 per cent. At present, the country has 9,68,377 active cases and as many as 45,87,614 people have been treated and discharged.

The number of people who recovered from Covid-19 stood at over 1.01 lakh on Monday, the highest single-day rise so far. The recovery rate stands at 80.86 per cent. With India recording the highest number of COVID-19 recoveries in the world, the government on Tuesday said that for the past four consecutive days the number of daily recovered cases surpassed the new infections reported per day.

Globally, as many as 31,480,193 people have been infected while 968,726 have succumbed to the virus. Also, 21,624,431 people have recovered so far.

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Coronavirus LIVE updates: India has over 56 lakh cases, over 90,000 deaths; recovery rate is 80.86 per cent; Globally, 31,480,193 people have been infected. Follow latest updates here

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Coronavirus India LIVE updates

The Central Drugs Standard Control Organisation (CDSCO), which released a new set of guidelines for Covid-19 vaccines on Monday, also emphasized that the statistical range of efficacy (the ability to produce the desired outcome) in the human trials cannot be lower than 30 per cent.

The guidelines come several months after the World Health Organization (WHO) and the US Food and Drug Administration (US FDA) released their own guidelines for Covid-19 vaccine approvals and draw from both documents, according to experts that have been closely tracking and involved in Covid-19 vaccine developments.

“To ensure that a widely deployed Covid-19 vaccine is effective, the primary efficacy endpoint point estimate for a placebo-controlled efficacy trial should be at least 50 percent, and the statistical success criterion should be that the lower bound of the appropriately alpha-adjusted confidence interval around the primary efficacy endpoint point estimate is (greater than) 30 percent,” stated CDSCO.

“What this essentially translates to is that the trial size has to be sufficient so that if the investigators get exactly 50 percent efficacy, we should have confidence that it will not be less than 30 percent,” said vaccine scientist and Christian Medical College, Vellore professor Dr Gagandeep Kang.

Meanwhile, marking its first big staff lay-offs since the Covid outbreak, the BCCI has decided to not renew the annual contracts of 11 coaches at its premier National Cricket Academy (NCA), including five retired India players —Ramesh Powar, SS Das, Hrishikesh Kanitkar, Subroto Banerjee and Sujith Somsundar.

The Indian Express has learnt that former India captain Rahul Dravid, who had handpicked the team after taking over as Head of Cricket at NCA, informed the coaches last week about the termination of their services. Those who have been asked to leave include domestic stalwart Sitanshu Kotak.

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